Just under 200 convenience stores are currently signed up to the government-funded scheme, which aims to boost fruit and vegetable consumption in deprived parts of the country.
Despite encouraging results, a Department of Health (DoH) spokeswoman told C-Store that all government campaigns, including Change4Life, would be looked at as part of its plan to cut public spending by £6bn.
As part of the scheme, "beacon" stores receive up to £2,500 from the DoH and their symbol groups in order to improve chilled equipment and bolster fruit and vegetable ranges.
Spar manager Carol Devlin, who runs a beacon store in Bristol, said it would be a "great shame" if the scheme was scrapped. "Fruit and veg sales have risen 30% on average since we launched Change4Life in April," she said.
Other projects potentially at risk include the Train to Gain training programme and funding for regional development agencies.